Cheap Flights From Philadelphia to South America

Active South America deals departing Philadelphia.

1 active deal

Guayaquil

Philadelphia → Guayaquil

$415 USDRoundtrip

$3,495.87 USD+$3,080.87 · checked 21h ago

Oct – Nov 2026 · American Airlines · 1 stop

Found yesterdaySee deal

Other regions from Philadelphia